SYSTEMIC
systemic
(adjective) affecting an entire system; “a systemic poison”
Source: WordNet® 3.1
Etymology
Adjective
systemic (not comparable)
Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.
(physiology) Pertaining to an entire organism.
Synonym: holistic
Usage notes
Not to be confused with systematic (“methodical”).
Antonyms
• topical
• (widespread, prevalent): endemic
Source: Wiktionary
Sys*tem"ic, a.
1. Of or relating to a system; common to a system; as, the systemic
circulation of the blood.
2. (Anat. & Physiol.)
Definition: Of or pertaining to the general system, or the body as a whole;
as, systemic death, in distinction from local death; systemic
circulation, in distinction from pulmonic circulation; systemic
diseases. Systemic death. See the Note under Death, n., 1.
Source: Webster’s Unabridged Dictionary 1913 Edition