OBLITERATION
annihilation, obliteration
(noun) destruction by annihilating something
eradication, obliteration
(noun) the complete destruction of every trace of something
Source: WordNet® 3.1
Noun
obliteration (countable and uncountable, plural obliterations)
The total destruction of something.
The cancellation, erasure or deletion of something.
(medicine) The cancellation of the function, structure, or both of a vessel or organ; for example, the occlusion of the lumen of a duct, blood vessel, or lymphatic vessel, be it solely functional (as when squeezed by nearby mass effect or inflammation) or both structural and functional (as when clogged with thrombus, embolus, or fibrosis).
Source: Wiktionary
Ob*lit`er*a"tion, n. Etym: [L. obliteratio: cf.F. oblitération.]
Definition: The act of obliterating, or the state of being obliterated;
extinction. Sir. M. Hale.
Source: Webster’s Unabridged Dictionary 1913 Edition