DERANGE

perturb, derange, throw out of kilter

(verb) throw into great confusion or disorder; “Fundamentalists threaten to perturb the social order”

unbalance, derange

(verb) derange mentally, throw out of mental balance; make insane; “The death of his parents unbalanced him”

Source: WordNet® 3.1

Etymology

Verb

derange (third-person singular simple present deranges, present participle deranging, simple past and past participle deranged)

(transitive, mostly, passive) To cause (someone) to go insane or become deranged.

(transitive) To cause disorder in (something); to distort from its ideal state.

(archaic) to disrupt somebody's plans, to inconvenience someone

Anagrams

• Redange, agender, angered, en garde, enraged, grandee, grenade

Source: Wiktionary

De*range", v. t. [imp. & p. p. Deranged; p. pr. & vb. n. Deranging.] Etym: [F. déranger; pref. dé- = dés- (L. dis) + ranger to range. See Range, and cf. Disarrange, Disrank.]

1. To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.

2. To disturb in action or function, as a part or organ, or the whole of a machine or organism. A sudden fall deranges some of our internal parts. Blair.

3. To disturb in the orderly or normal action of the intellect; to render insane.

Syn.

– To disorder; disarrange; displace; unsettle; disturb; confuse; discompose; ruffle; disconcert.

Source: Webster’s Unabridged Dictionary 1913 Edition